Mifegymiso (Mifepristone Misoprostol)

Additional information

Mifegymiso (Mifepristone Misoprostol) is typically taken based on a regimen. Step 1 (Green Box): Mifepristone is taken first to block a hormone that is needed for your pregnancy to continue. Swallow the tablet with a glass of water. Step 2 (Orange Box): Misoprostol is the second drug. It is taken 24-48 hours later. Place the 4 Misoprostol tablets in your mouth. Keep the 4 tablets between your cheeks and gums for 30 minutes. Then, swallow any fragments that are left with water. Plan to rest for 3 hours after taking the Misoprostol tablets. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. If you forget a dose, contact your pharmacist.

WARNING: Once you start Mifegymiso, you should complete both steps. Both Mifepristone and Misoprostol can cause birth defects if your pregnancy is continued. Prolonged heavy bleeding may be a sign of incomplete abortion or other complications, prompt medical or surgical intervention may be needed. Patients must seek immediate medical attention. You must have a follow-up appointment with a health professional, 7 to 14 days after Step 1 (taking the mifepristone tablet from the green box). The health professional will check whether your pregnancy has completely ended. If the pregnancy continues, there is a possibility of birth defects. Your health professional will talk with you about your options. To decrease the chance of birth defects, avoid getting pregnant again before your next period. This will protect the baby from any exposure to Mifegymiso. Use birth control during this one month waiting period.

In addition to its desired action, Mifegymiso (Mifepristone Misoprostol) may cause some side effects, notably:
It may cause breast tenderness, chills, diarrhea
It may cause dizziness, fatigue, headache

Contraindications: Hypersensitivity to mifepristone, misoprostol, other prostaglandins, or any component of the formulation, ectopic pregnancy (when a fertilised egg implants itself outside of the womb, usually in one of the fallopian tubes), presence of intrauterine (inside the womb) device (IUD), unconfirmed gestational age, chronic adrenal failure (a condition in which the adrenal glands found on top of the kidneys do not produce enough of the adrenal hormones that control important functions such as blood pressure), concurrent long term corticosteroid therapy, hemorrhagic (bleeding) disorders or using concurrent anticoagulation therapy, inherited porphyria (a group of disorders that result from a buildup of natural chemicals that produce porphyrin in your body. Porphyrins are essential for the function of hemoglobin — a protein in your red blood cells that links to porphyrin, binds iron, and carries oxygen to your organs and tissues), uncontrolled asthma (a respiratory condition marked by attacks of spasm in the bronchi of the lungs, causing difficulty in breathing).

Taking Mifegymiso (Mifepristone Misoprostol) during pregnancy is contraindicated and harmful for the baby. Women of childbearing potential should use an effective contraceptive method.Pregnant women should not use this product. If you're planning a pregnancy or become pregnant or breastfeeding, contact your family doctor.

A treatment with Mifegymiso (Mifepristone Misoprostol) requires regular monitoring by a doctor. Be sure to see your doctor for all regularly scheduled appointments.Mifegymiso (Mifepristone Misoprostol)