Name: Soliris (Eculizumab)
SKU: EU/1/07/393/001
Availability: OutOfStock

Description

Soliris (Eculizumab) is a monoclonal antibody agent. It is typically used to treat PNH and aHUS. These are rare and serious conditions where the immune system is attacking the body’s own cells: paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). In these conditions, the immune system causes red blood cells to break down too early, leading to anemia (low blood cells), fatigue, and other serious health issues. It may also have other uses.

Additional information

"Soliris (Eculizumab) is usually given as an injection as follows, depending on the condition: The usual dose of SOLIRIS for PNH patients is:600 mg of SOLIRIS every 7 days for the first 4 weeks, followed by 900 mg of SOLIRIS for the fifth dose 1 week later, then 900 mg of SOLIRIS every 2 weeks thereafter. The usual dose of SOLIRIS for adult patients with atypical HUS is: 900 mg of SOLIRIS weekly for the first 4 weeks, followed by 1200 mg of SOLIRIS for the fifth dose 1 week later, then 1200 mg of SOLIRIS every 2 weeks thereafter. However, your doctor or pharmacist may suggest a different schedule that is more suitable for you. Important: Follow the instructions on the label. Do not take more of this product or take it more often than prescribed. If you miss a dose, contact your pharmacist. SOLIRIS is given through a vein, usually over 35 minutes, and must be administered by a health care professional

WARNING: Serious allergic reactions can happen during your SOLIRIS infusion. Fungal infections caused by Aspergillus have occurred in immunocompromised patients with abnormally low white blood cells. Inform your doctor before you take SOLIRIS if you have any infections.

In addition to its desired action, this medication may cause some side effects, notably:
It may cause a sudden or severe drop in your red blood cell count causing anemia, confusion or drowsiness, chest pain
It may cause stroke, confusion, seizure

Contraindications: Do not use this medication if you have a known allergy (hypersensitivity) to any of its ingredients. Do not take this medication if your doctor confirms a serious infection, such as an active Neisseria meningitidis infection(in the brain, spinal cord or blood) and if you have not received a meningococcal vaccine prior to or at the time of initiating

Taking this medication during pregnancy is contraindicated and harmful for the baby. Women of childbearing potential should use an effective contraceptive method. Pregnant women should not use this product. If you're planning a pregnancy or become pregnant or breastfeeding, contact your family doctor.

A treatment with this medication requires regular monitoring by a doctor. Be sure to see your doctor for all regularly scheduled appointments."

Warning

Each person may react differently to a treatment. If you think this medication may be causing side effects (including those described here, or others), talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.