Advagraf (Tacrolimus extended-release)

Description

Advagraf (Tacrolimus extended-release) is an immunosuppressant agent. It is typically used for the prevention of organ rejection in kidney and liver transplant recipients in combination with other immunosuppressants. It may also have other uses.

Additional information

Advagraf (Tacrolimus extended-release) is typically taken once daily. For kidney or liver transplants, the dose of tacrolimus varies according to the circumstances. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed. If you forget a dose, contact your pharmacist. Administer with or without food, but it is best to be consistent. Tacrolimus should not be taken with grapefruit or grapefruit juice. The capsules should be swallowed whole and not cut, crushed, or chewed, you should try to take your dose of tacrolimus at the same time every day.

WARNING: Immunosuppressant agents, including tacrolimus, increase the risk of infection and it may be associated with the development of malignancies (cancers) that may lead to hospitalization or death

In addition to its desired action, Advagraf (Tacrolimus extended-release) may cause some side effects, notably:
It may cause constipation, diarrhea
It may cause difficulty sleeping or nightmares, headache
It may cause fatigue, trembling, weakness

Contraindications: Hypersensitivity to tacrolimus, polyoxyl 60 hydrogenated castor oil (HCO-60), or any other component of the formulation.

Taking Advagraf (Tacrolimus extended-release) during pregnancy may be harmful for the baby. Women of childbearing potential should use an effective contraceptive method. Pregnant women should not use this product. If you're planning a pregnancy or become pregnant or breastfeeding, contact your family doctor.

A treatment with Advagraf (Tacrolimus extended-release) requires regular monitoring by a doctor. Be sure to see your doctor for all regularly scheduled appointments.Advagraf (Tacrolimus extended-release)

Warning

Each person may react differently to a treatment. If you think this medication may be causing side effects (including those described here, or others), talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.