PPC Pamidronate Disodium (Pamidronate)
Brand: PPC Pamidronate Disodium
Active Ingredient(s): Pamidronate
Strength: 3 mg / mL – 6 mg / mL – 9 mg / mL
Pack Size: 10 mL – 10 mL – 10 mL Injectable
Store at room temperature.
DIN: 02246597 – 02246598 – 02246599
Manufacturer: Fresenius Kabi (Canada)
Alternatives: Jamp Pamidronate Disodium – Omega Pamidronate Disodium – Pamidronate Disodium
*A valid prescription is required for Rx items.
Description
PPC Pamidronate Disodium (Pamidronate) is a bisphosphonate (reduces the breakdown of bones). It is typically used to treat hypercalcemia (high blood calcium) in people who have cancer or cancer that has spread to bones (bone metastases), due to different types of tumors. It is also used to treat the symptoms of Paget’s disease (disease of the bones). It may also have other uses.
Additional information
PPC Pamidronate Disodium (Pamidronate)'s dosage depends on the condition being treated (usual range: 60 mg - 90 mg). Single doses should not exceed 90 mg. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. It will be given to you by a doctor or nurse in a hospital or clinical setting. It is given via intravenous (IV, into the veins) infusion at different rates depending on the condition. Longer infusion times (>2 hours) may reduce the risk of kidney toxicity, especially in patients with pre-existing kidney impairment. WARNING: Pamidronate may contribute to a type of rare fracture of the long bone in the thigh (femur). On rare occasions, people Taking PPC Pamidronate Disodium (Pamidronate) experience severe bone, joint, or muscle pain. This is usually reversed when the medication is stopped. People with cancer treated with pamidronate may develop osteonecrosis of the jaw (deterioration of the jaw bone). It may cause drowsiness and dizziness. Avoid driving, operating potentially dangerous machinery, or participating in other activities that may be hazardous. Decreased kidney function and kidney disease may cause pamidronate to build up in the body, leading to side effects, use with caution. This medication may also cause kidney problems. In addition to its desired action, PPC Pamidronate Disodium (Pamidronate) may cause some side effects, notably: It may cause flu-like symptoms (fever, chills, muscle pain), increased tear production, difficulty sleeping, and muscle or joint pain. It may cause nausea, vomiting, constipation, diarrhea, stomach pain, headache, and dizziness. It may cause blood pressure changes (increase or decrease), heart rhythm changes, irregular heart beat, and numbness or tingling in the hands, feet or lips. It may cause increased frequency of infection, decreased vision, eye pain or irritation, and sensitivity to light. Contraindications: Hypersensitivity to pamidronate, other bisphosphonates (same class as pamidronate), or any component of the formulation. Taking PPC Pamidronate Disodium (Pamidronate) during pregnancy may be harmful for the baby. Women of childbearing potential should use an effective contraceptive method. Pregnant women should not use this product. If you're planning a pregnancy or become pregnant or breastfeeding, contact your family doctor. A treatment with PPC Pamidronate Disodium (Pamidronate) requires regular monitoring by a doctor. Be sure to see your doctor for all regularly scheduled appointments.PPC Pamidronate Disodium (Pamidronate)
Warning
Each person may react differently to a treatment. If you think this medication may be causing side effects (including those described here, or others), talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.
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