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Translarana (ataluren)

Brand: Translarana
Active Ingredient(s): ataluren
Pack Size: 30 – 30 – 30 sachets for oral solution
Store in the refrigerator.
DIN:
Manufacturer: PTC Therapeutics International Limited (EU)
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Description

Translarana (Ataluren) is an agent used to treat a genetic condition. It is typically used to treat Duchenne muscular dystrophy in children 5 years of age and older who have a specific genetic mutation known as a nonsense mutation in the dystrophin gene. This disease causes muscle weakness and loss of function due to a lack of a protein called dystrophin. In DMD, a genetic mutation prevents the production of dystrophin, leading to the breakdown of muscle tissue over time. It may also have other uses.

Additional information

Translarana (Ataluren) is usually taken three times daily. However, your doctor or pharmacist may suggest a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not take more of this product, or take it more often, than prescribed. If you miss a dose, contact your pharmacist. It can be taken with food.

WARNING: If you have severe kidney problems or if you are receiving dialysis because your kidneys do not work (end-stage renal disease) your doctor will establish if treatment with Translarna is suitable for you. Your doctor will test the levels of lipids (fats such as cholesterol and triglycerides) in your blood and
your kidney function every 6 to 12 months. 

In addition to its desired action, this medication may cause some side effects, notably:

It may cause vomiting, diarrhea, nausea, headache
It may cause stomach upset or pain, gas (flatulence), decreased appetite, weight loss

Contraindications: Do not use this medication if you have a known allergy (hypersensitivity) to any of its ingredients. Concomitant use of intravenous aminoglycosides (antibiotics)

Taking this medication during pregnancy is contraindicated and harmful for the baby. Women of childbearing potential should use an effective contraceptive method. Pregnant women should not use this product. If you're planning a pregnancy or become pregnant or breastfeeding, contact your family doctor.

A treatment with this medication requires regular monitoring by a doctor. Be sure to see your doctor for all regularly scheduled appointments.

Warning

Each person may react differently to a treatment. If you think this medication may be causing side effects (including those described here, or others), talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.

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